COMPOUNDED SERMORELIN IMPORTANT SAFETY INFORMATION

Date of Last Revision: 08.12.2025

Compounded drugs are permitted to be prescribed under federal law but are not FDA-approved and do not undergo the same safety, effectiveness, or manufacturing review as FDA-approved medications. Your medical provider may recommend certain doses of compounded sermorelin based on your medical evaluation.

Indications and Use

Compounded sermorelin is a prescription peptide that may be prescribed by a licensed healthcare professional to qualifying adult patients as part of a personalized care plan. Sermorelin is a growth hormone–releasing hormone (GHRH) analog that stimulates the body’s natural production of growth hormone. It may be used to address growth hormone deficiency and support related wellness goals as determined by your provider.

Sermorelin should be used exactly as prescribed and is typically combined with healthy lifestyle measures such as regular exercise, balanced nutrition, and adequate sleep.

Important Safety Information for Compounded Sermorelin

Do NOT use compounded sermorelin if you:

• Have a known allergy to sermorelin or any of its ingredients
• Have active cancer or a history of certain tumors unless approved by your healthcare provider
• Are pregnant, planning to become pregnant, or breastfeeding

Before using compounded sermorelin, tell your healthcare provider if you:

• Have a history of pituitary tumors or pituitary surgery
• Have thyroid disease, diabetes, or any chronic medical conditions
• Are taking prescription or over-the-counter medicines, vitamins, or herbal supplements
• Have a history of breathing problems or sleep apnea

How to Take

• Read the Instructions for Use provided with your medication before starting sermorelin.
• Sermorelin is usually injected subcutaneously (under the skin) once daily at bedtime, as an oral tablet or as directed by your provider.
• For subcutaenous injection, rotate injection sites to reduce skin irritation.
• Do not change your dose or stop treatment without consulting your healthcare provider.

Possible Side Effects

Common side effects may include:

• Injection site redness, swelling, or pain
• Headache
• Flushing
• Difficulty swallowing
• Dizziness

Less common but more serious side effects may include:

• Allergic reactions (rash, itching, swelling of the face/tongue/throat, trouble breathing)
• Joint pain
• Fluid retention or swelling in hands/feet
• Carpal tunnel–like symptoms (numbness or tingling in hands/wrists)

Call your healthcare provider immediately if you experience signs of a severe allergic reaction, new or worsening shortness of breath, or swelling that does not resolve.

Pregnancy and Breastfeeding

Sermorelin has not been studied in pregnant or breastfeeding women. It should not be used during pregnancy, and it is not known if sermorelin passes into breast milk. Inform your provider if you become pregnant or are breastfeeding while on therapy.

Storage and Handling

• Store as instructed by your pharmacy (often refrigerated).
• Keep out of reach of children and pets.
• Do not share needles or medication with others.

Disclaimer: Compounded sermorelin is not FDA approved. This information is not a substitute for professional medical advice. Always talk with your healthcare provider about whether compounded sermorelin is appropriate for you, how to take it, and how to monitor for side effects.

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