Enclomiphene citrate 12.5 mg or 25 mg capsules
Compounded medications are prepared by state-licensed pharmacies. Prescription only — available if a licensed provider determines treatment is appropriate after your online visit. Not available in all states.
Lab work is billed separately at a flat $115 per session (before starting and every 90 days). No insurance, no membership fees, no auto-renewal.
Enclomiphene is the active isomer of clomiphene, a selective estrogen receptor modulator. It blocks estrogen's feedback signal at the hypothalamus and pituitary, which raises luteinizing hormone (LH) and follicle-stimulating hormone (FSH), the messengers that tell the testes to produce testosterone and sperm. Within a few weeks total testosterone typically rises into the normal range while sperm production continues, the key difference from testosterone replacement, which switches those signals off.
Enclomiphene is compounded by a licensed U.S. pharmacy for your prescription and is not FDA-approved. Treatment is for men with secondary (pituitary-signaling) low testosterone confirmed by labs.
Most men start at 12.5 mg once daily, taken at the same time each day with or without food. Your 90-day labs measure total and free testosterone, LH, FSH, estradiol and hematocrit; your provider may increase to 25 mg or adjust the schedule based on the results and your symptoms. The 3-month plan covers 90 days; the 6-month plan covers 180 at the lowest monthly cost.
Enclomiphene is for adult men, including those under 35, with lab-confirmed low testosterone whose pituitary signaling is intact, who want to support natural production, are concerned about fertility, prefer an oral option and are comfortable with ongoing lab monitoring. It's also used by men coming off testosterone replacement who want to restart their own production.
Men with primary testicular failure (high LH with low testosterone) usually don't respond and are better served by testosterone replacement. Your provider will tell you which applies after reviewing your labs.
Weeks 1–4. LH and FSH rise within days and testosterone begins climbing. Many men notice improved energy, mood and libido by the end of the first month.
Months 2–3. Testosterone typically settles into the normal range. Sleep, motivation and workout recovery improve, and your 90-day labs confirm the response and guide any dose change.
Months 3–6. Strength and body-composition changes build with training. Your provider fine-tunes the dose from your labs; some men step up to 25 mg.
Ongoing. Enclomiphene supports your own production for as long as you take it, with quarterly labs. If you stop, levels gradually return toward baseline.
Answers from the GobyMeds care team. Still have a question? Your provider can answer it during your online visit.
Enclomiphene blocks estrogen's feedback at the hypothalamus and pituitary, which raises LH and FSH, the hormones that tell your testes to produce testosterone and sperm. Testosterone typically rises into the normal range within a few weeks while fertility is preserved, which is the key difference from replacement therapy.
Most men tolerate it well. Reported effects include headache, hot flashes, nausea, mood changes, acne and, rarely, visual disturbances such as blurring or spots; stop and contact your provider if you notice vision changes. Enclomiphene is a compounded medication and is not FDA-approved.
Most men start at 12.5 mg once daily; your provider may increase to 25 mg based on your 90-day labs and symptoms. Capsules are taken at the same time each day with or without food.
Testosterone replacement therapy restores testosterone to a healthy range in men whose levels are low and who have symptoms such as persistent fatigue, low libido, loss of muscle, brain fog, low mood or poor sleep and recovery. GobyMeds confirms low testosterone with a blood test before any prescription is written, and your provider reviews both your labs and your symptoms.
A comprehensive panel is required before starting and every 90 days while you're on treatment. We charge a flat $115 per lab session, which covers the blood draw at a lab near you and your provider's review, about $38 a month. Labs are the only cost outside your plan price; there are no membership or hidden fees.
Testosterone replacement (injections, hypospray and cream) suppresses the signals that drive sperm production, so it can reduce fertility while you're on it and is not recommended if you may want children soon. Enclomiphene works differently: it raises your own testosterone by stimulating those signals, which is why it's the usual choice for younger men and those keeping fertility in the picture. Talk this through with your provider before choosing a path.
Yes. A team of licensed U.S. providers reviews your initial labs, writes your protocol, checks your follow-up labs every three months and is available by message between visits. Dose changes are made based on your levels and how you feel, not a fixed schedule.
Testosterone Support uses enclomiphene, a once-daily capsule that prompts your pituitary to signal your testes to make more testosterone, so your natural production is preserved. TRT delivers testosterone directly as an injection, spray or cream and is built for men 35 and older whose production is unlikely to recover. A licensed provider reviews your labs and helps you choose.
If a GobyMeds provider decides a prescription isn't appropriate for you, you receive a 100% refund of the medication price (lab fees, where they apply, are not refunded). Once your order has been sent to our medical partners or to the pharmacy for fulfillment we will do our best to accommodate changes or cancellations, but we can't guarantee them, and in some cases an adjustment or cancellation carries a $50 medical consultation fee.
Because of regulations covering prescription medication, we are unable to accept returned medication for a refund.
No insurance is needed and GobyMeds does not bill insurance. The price you see is the price you pay, with provider consultation and shipping included and no membership fee.
HSA and FSA cards are accepted at checkout, and we can provide a letter of medical necessity if your plan administrator asks for one.
You answer a short health questionnaire and upload a photo ID. A licensed U.S. provider reviews your history, confirms the treatment is appropriate, and writes the prescription. There is no video call to schedule unless your provider or your state requires one, and follow-up messaging with your care team is included with every plan.
If you're not a candidate, you'll be told why and refunded in full.
Oral enclomiphene (12.5 or 25 mg) to support your body’s own testosterone production without exogenous testosterone.
Start your online visitMost men tolerate enclomiphene well. Reported side effects include headache, hot flashes, nausea, mood changes or irritability, acne, increased libido and, less commonly, a rise in hematocrit or estradiol, which your 90-day labs track. Rarely, clomiphene-class medications cause visual disturbances such as blurring, spots or light sensitivity; stop and contact your provider if you notice vision changes.
Enclomiphene is a compounded medication and is not FDA-approved. Report side effects to the FDA at 1-800-FDA-1088.
Enclomiphene is not prescribed to men with liver disease, a history of hormone-sensitive cancer, uncontrolled thyroid or adrenal disease, a pituitary tumor, or a history of blood clots, and it is not for women. Tell your provider about vision problems, depression and all medications you take. Prescription only; available only when a licensed provider determines it is appropriate after reviewing your labs. Not available in all states.
This page is for informational purposes and does not replace a consultation with a licensed provider. Compounded medications are not reviewed by the FDA for safety, effectiveness, or quality. Brand names are trademarks of their respective owners; GobyMeds is not affiliated with them.
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