
Nicotinamide adenine dinucleotide (NAD+) 100-200 mg/mL injection
Compounded medications are prepared by state-licensed pharmacies. Prescription only — available if a licensed provider determines treatment is appropriate after your online visit. Not available in all states.
No insurance, no membership fees, no auto-renewal.
NAD+ sits at the center of cellular metabolism: it shuttles electrons in the mitochondria to produce ATP, fuels the sirtuin enzymes linked to healthy aging and DNA repair, and is consumed by PARP enzymes when cells repair damage. As NAD+ falls with age, cells have less capacity to make energy and repair themselves, which shows up as fatigue, brain fog and slower recovery.
Injecting NAD+ under the skin bypasses digestion, where oral NAD+ is largely broken down, and delivers it directly to the bloodstream. The subcutaneous route lets you dose at home two to three times a week instead of sitting through hours-long IV infusions. Compounded NAD+ is prepared by a licensed U.S. pharmacy and is not FDA-approved.
Your provider sets a starting dose, typically 25–50 mg, injected under the skin of the abdomen or thigh two to three times a week on non-consecutive days. Injecting slowly reduces the brief flushing some people feel. The vial is kept refrigerated and drawn with the supplied insulin-type syringes.
The dose can be adjusted after your first few weeks based on how you feel and tolerate it; a 1-month plan covers 4 weeks and a 3-month plan covers 12.
NAD+ injection is for adults dealing with persistent fatigue or brain fog, people focused on healthy aging, performance or metabolic health, and those recovering from burnout, illness or chronic stress. It's commonly combined with GLP-1 weight-loss medication, sermorelin or TRT, and it's the right choice for anyone comfortable with a small self-injection who wants precise dosing.
If you'd rather avoid needles, the NAD+ nasal spray delivers the same molecule daily. NAD+ is not for use during pregnancy or breastfeeding.

Weeks 1–4. Many patients report steadier daytime energy, clearer thinking and a lift in mood within the first two to four weeks as cellular NAD+ levels rise.
Month 2. Deeper sleep, faster recovery from exercise and a more stable metabolism are commonly reported as the effect builds.
Month 3. The fuller effect on sustained mental performance, recovery and metabolic markers is typically felt by the end of the third month of consistent use.
Ongoing. NAD+ is a support therapy: benefits continue with regular dosing and your provider can adjust the dose or schedule at any follow-up.

Answers from the GobyMeds care team. Still have a question? Your provider can answer it during your online visit.
You draw the prescribed dose from a multi-dose vial and inject it under the skin of the abdomen or thigh, two to three times a week on non-consecutive days. Injecting slowly reduces the brief flushing some people feel. Supplies and step-by-step instructions are included, and the vial is kept refrigerated.
Most patients use 25–50 mg per injection. Your provider sets the starting dose and may adjust it after your first few weeks based on how you feel and tolerate it.
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell that mitochondria use to turn food into energy; it's also required for DNA repair and for the sirtuin enzymes linked to healthy aging. Levels decline with age and under chronic stress, and supplementing NAD+ directly is intended to restore the pool your cells draw on.
Many patients report steadier energy and clearer thinking within two to four weeks, with the fuller effect on sleep, recovery and mood building over two to three months of consistent use. NAD+ is a support therapy rather than a cure, and results vary from person to person.
Most people experience few or none. Mild flushing, headache, nausea or fatigue can occur during or shortly after a dose, and injections may cause redness or tenderness at the site. Less commonly people report muscle cramping, stomach upset or a jittery, anxious feeling; slowing the injection or lowering the dose usually resolves it. Serious reactions are very rare.
Yes. NAD+ is commonly used alongside GLP-1 weight-loss medication, sermorelin and TRT, since it works on cellular energy rather than hormones. Tell your provider everything you take, including supplements, so your plan can be coordinated.
The subcutaneous injection delivers a precise 25–50 mg dose two or three times a week and is the more economical option on a 3-month plan. The nasal spray is needle-free, taken daily, and suits people who want convenience or dislike injections. Your provider can start you on either and switch later.
No. Compounded NAD+ is prepared by licensed U.S. pharmacies for an individual prescription and is not FDA-approved or FDA-reviewed for safety or effectiveness. Human research on NAD+ supplementation is still emerging, which is why GobyMeds pairs it with provider oversight rather than selling it over the counter.
If a GobyMeds provider decides a prescription isn't appropriate for you, you receive a 100% refund of the medication price (lab fees, where they apply, are not refunded). Once your order has been sent to our medical partners or to the pharmacy for fulfillment we will do our best to accommodate changes or cancellations, but we can't guarantee them, and in some cases an adjustment or cancellation carries a $50 medical consultation fee.
Because of regulations covering prescription medication, we are unable to accept returned medication for a refund.
No insurance is needed and GobyMeds does not bill insurance. The price you see is the price you pay, with provider consultation and shipping included and no membership fee.
HSA and FSA cards are accepted at checkout, and we can provide a letter of medical necessity if your plan administrator asks for one.
You answer a short health questionnaire and upload a photo ID. A licensed U.S. provider reviews your history, confirms the treatment is appropriate, and writes the prescription. There is no video call to schedule unless your provider or your state requires one, and follow-up messaging with your care team is included with every plan.
If you're not a candidate, you'll be told why and refunded in full.
Compounded NAD+ subcutaneous injection, typically 25-50 mg per dose, for cellular energy and longevity support.
Start your online visitMost people experience few or no side effects. Mild flushing, headache, nausea or fatigue can occur during or shortly after a dose, and less commonly people report muscle cramping, stomach upset or a jittery, anxious feeling; a slower injection or a lower dose usually resolves it. Serious reactions are very rare. NAD+ is a naturally occurring coenzyme, but compounded NAD+ is not FDA-approved and human research on supplementation is still emerging.
Injection-specific effects include redness, tenderness or a small bump at the injection site; rotate sites and inject slowly.
NAD+ is not prescribed during pregnancy or breastfeeding, to anyone with a known allergy to the formulation, or to people with uncontrolled heart disease or active cancer unless cleared by their treating physician. Tell your provider about liver or kidney disease, blood pressure medication and all supplements you take.
This page is for informational purposes and does not replace a consultation with a licensed provider. Compounded medications are not reviewed by the FDA for safety, effectiveness, or quality. Brand names are trademarks of their respective owners; GobyMeds is not affiliated with them.