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NAD+ Nasal Spray
Compounded NAD+ nasal spray bottle from GobyMeds
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NAD+ Nasal Spray

Nicotinamide adenine dinucleotide (NAD+) 300 mg/mL nasal spray, 15 mL

300 mg/mL, 15 mL
Nasal spray
From
$
199
/month
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as little as 3 days

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One-time purchase · no auto-renewal

1-Month Supply

300 mg/mL, daily
$
199
$
199
/mo
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One-time purchase. Ships once, no recurring billing.
Compounded NAD+ 300 mg/mL nasal spray, 15 mL; refrigerate. Not FDA-approved.

Compounded medications are prepared by state-licensed pharmacies. Prescription only — available if a licensed provider determines treatment is appropriate after your online visit. Not available in all states.

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Licensed providers and support staff, reachable by chat and email.
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Every order is reviewed by a licensed provider before it ships.

What every plan includes

  • Online visit and ongoing follow-ups with a licensed U.S. provider
  • Compounded NAD+ nasal spray 300 mg/mL, 15 mL (one-month supply)
  • Dosing instructions and usage guide
  • Free refrigerated shipping to your door
  • Support from the GobyMeds care team by chat, text and email

No insurance, no membership fees, no auto-renewal.

How it works

NAD+ powers the mitochondrial reactions that produce ATP, fuels the sirtuin enzymes tied to healthy aging and is consumed when cells repair DNA. Levels decline with age and under chronic stress, which is felt as fatigue, slower recovery and brain fog. Supplementing restores the pool cells draw on.

The nasal lining is thin and richly supplied with blood vessels, so NAD+ sprayed into the nose is absorbed directly rather than being broken down in the gut like oral supplements. Less of each dose reaches the bloodstream than with an injection, which is why the spray is taken daily. Compounded NAD+ is prepared by a licensed U.S. pharmacy and is not FDA-approved.

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Dosing & Titration

Prime the pump before first use, tilt your head slightly forward and spray the prescribed number of pumps into each nostril once daily, breathing in gently. Store the bottle in the refrigerator between uses. A 15 mL bottle at 300 mg/mL is a one-month supply at the standard dose; your provider can adjust the dose at any follow-up.

Key benefits

  • Needle-free NAD+ with no injections or IV appointments
  • Absorbed through the nasal lining, bypassing digestion
  • Simple once-daily routine that travels easily
  • Supports cellular energy, mental clarity and recovery
  • Prescribed and followed up by licensed U.S. providers, 100% online

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Plans from $
199
/mo
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Who it's for

NAD+ nasal spray is for adults dealing with fatigue or brain fog, people focused on healthy aging, performance or metabolic health, and anyone who wants NAD+ support but prefers to avoid needles. It pairs well with GLP-1 weight-loss medication, sermorelin and TRT.

If you want the most economical option or precise dosing, the NAD+ injection delivers more per dose on a 3-month plan. The spray is not for use during pregnancy or breastfeeding, or if you have chronic nasal congestion that would limit absorption.

For men
For women

What to expect, month by month

Weeks 1–4. Many patients report steadier daytime energy, clearer thinking and a lift in mood within the first two to four weeks as cellular NAD+ levels rise.

Month 2. Deeper sleep, faster recovery from exercise and a more stable metabolism are commonly reported as the effect builds.

Month 3. The fuller effect on sustained mental performance, recovery and metabolic markers is typically felt by the end of the third month of consistent use.

Ongoing. NAD+ is a support therapy: benefits continue with regular dosing and your provider can adjust the dose or schedule at any follow-up.

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Frequently asked questions

Answers from the GobyMeds care team. Still have a question? Your provider can answer it during your online visit.

How do I use the NAD+ nasal spray?

Prime the pump, tilt your head slightly forward and spray the prescribed number of pumps into each nostril once daily, breathing in gently. Each 15 mL bottle at 300 mg/mL is a one-month supply at the standard dose. Store it in the refrigerator between uses.

Does the nasal spray work as well as the injection?

Intranasal delivery bypasses digestion and is absorbed through the nasal lining, but less of each dose reaches the bloodstream than with an injection, so daily use is important. Many patients choose it for convenience or because they prefer a needle-free option; if you don't notice a benefit after two to three months, your provider can move you to the injection.

What is NAD+ and why do levels matter?

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell that mitochondria use to turn food into energy; it's also required for DNA repair and for the sirtuin enzymes linked to healthy aging. Levels decline with age and under chronic stress, and supplementing NAD+ directly is intended to restore the pool your cells draw on.

How long does it take to notice anything?

Many patients report steadier energy and clearer thinking within two to four weeks, with the fuller effect on sleep, recovery and mood building over two to three months of consistent use. NAD+ is a support therapy rather than a cure, and results vary from person to person.

What are the possible side effects?

Most people experience few or none. Mild flushing, headache, nausea or fatigue can occur during or shortly after a dose, and injections may cause redness or tenderness at the site. Less commonly people report muscle cramping, stomach upset or a jittery, anxious feeling; slowing the injection or lowering the dose usually resolves it. Serious reactions are very rare.

Can I combine NAD+ with other treatments like GLP-1s or sermorelin?

Yes. NAD+ is commonly used alongside GLP-1 weight-loss medication, sermorelin and TRT, since it works on cellular energy rather than hormones. Tell your provider everything you take, including supplements, so your plan can be coordinated.

Injection or nasal spray: which is right for me?

The subcutaneous injection delivers a precise 25–50 mg dose two or three times a week and is the more economical option on a 3-month plan. The nasal spray is needle-free, taken daily, and suits people who want convenience or dislike injections. Your provider can start you on either and switch later.

Is NAD+ FDA-approved?

No. Compounded NAD+ is prepared by licensed U.S. pharmacies for an individual prescription and is not FDA-approved or FDA-reviewed for safety or effectiveness. Human research on NAD+ supplementation is still emerging, which is why GobyMeds pairs it with provider oversight rather than selling it over the counter.

What is your cancellation and refund policy?

If a GobyMeds provider decides a prescription isn't appropriate for you, you receive a 100% refund of the medication price (lab fees, where they apply, are not refunded). Once your order has been sent to our medical partners or to the pharmacy for fulfillment we will do our best to accommodate changes or cancellations, but we can't guarantee them, and in some cases an adjustment or cancellation carries a $50 medical consultation fee.

Because of regulations covering prescription medication, we are unable to accept returned medication for a refund.

Do I need insurance, and can I use my HSA or FSA?

No insurance is needed and GobyMeds does not bill insurance. The price you see is the price you pay, with provider consultation and shipping included and no membership fee.

HSA and FSA cards are accepted at checkout, and we can provide a letter of medical necessity if your plan administrator asks for one.

How does the online visit work?

You answer a short health questionnaire and upload a photo ID. A licensed U.S. provider reviews your history, confirms the treatment is appropriate, and writes the prescription. There is no video call to schedule unless your provider or your state requires one, and follow-up messaging with your care team is included with every plan.

If you're not a candidate, you'll be told why and refunded in full.

NAD+ Nasal Spray

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Compounded NAD+ nasal spray (300 mg/mL, 15 mL): a needle-free NAD+ option.

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Free online visit · No membership · Cancel anytime before your order ships

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Medically reviewed by
GobyMeds Clinical Team
·
September 30, 2026

Important safety information

Side effects and precautions

Most people experience few or no side effects. Mild flushing, headache, nausea or fatigue can occur during or shortly after a dose, and less commonly people report muscle cramping, stomach upset or a jittery, anxious feeling; a slower injection or a lower dose usually resolves it. Serious reactions are very rare. NAD+ is a naturally occurring coenzyme, but compounded NAD+ is not FDA-approved and human research on supplementation is still emerging. Report side effects to the FDA at 1-800-FDA-1088.

Spray-specific effects include brief nasal stinging, a runny nose or an unusual taste just after dosing, which usually fade within minutes.

Who should not use it

NAD+ is not prescribed during pregnancy or breastfeeding, to anyone with a known allergy to the formulation, or to people with uncontrolled heart disease or active cancer unless cleared by their treating physician. Tell your provider about liver or kidney disease, blood pressure medication and all supplements you take. Compounded drug products are not approved or evaluated for safety, effectiveness or quality by the FDA. Prescription only; not available in all states. Tell your provider about chronic sinus disease, nasal surgery or frequent nosebleeds.

This page is for informational purposes and does not replace a consultation with a licensed provider. Compounded medications are not reviewed by the FDA for safety, effectiveness, or quality. Brand names are trademarks of their respective owners; GobyMeds is not affiliated with them.