Compounded medications are prepared by state-licensed pharmacies. Prescription only — available if a licensed provider determines treatment is appropriate after your online visit. Not available in all states.Pricing and dose progression vary by bundle and are subject to availability and final treatment selection.
Thymosin beta-4 fragment (TB-500) injection
TB-500 is for adults recovering from muscle, tendon, or ligament injuries, people training hard who want to recover faster between sessions, and anyone with several nagging soft-tissue complaints rather than one. It is also considered for post-surgical recovery and stubborn joint inflammation. Because it is dosed only once or twice a week after loading, it suits people who would rather not inject daily. It is frequently prescribed alongside BPC-157.
It is not for anyone with active cancer or a history of certain tumors, or during pregnancy or breastfeeding. TB-500 has been on the World Anti-Doping Agency prohibited list since 2012, so drug-tested athletes should not use it. Your provider reviews your history during the online visit.
No insurance, no membership fees, no auto-renewal.
Every cell moves by rearranging an internal scaffold made of a protein called actin, and thymosin beta-4 is the molecule that manages the free supply of actin building blocks. By binding those blocks, TB-500 helps the cells responsible for repair, including endothelial cells, keratinocytes, and tissue stem cells, migrate to an injury. Along the way it promotes new blood-vessel formation, lowers inflammatory cytokines and neutrophil infiltration, regulates the enzymes that remodel scar tissue, and encourages organized rather than fibrous collagen. In animal and cell studies it has also activated cardiac progenitor cells and hair-follicle stem cells.
Because TB-500 travels through the body rather than acting only where it is injected, it is prescribed for recovery that is not limited to one spot: generalized soreness, multiple nagging injuries, or post-surgical healing. The strongest human evidence is for the full protein in cardiac and ophthalmic trials; most musculoskeletal evidence is preclinical and veterinary, and your provider will say so.
TB-500 is usually taken in two phases. During a loading phase of four to six weeks your provider typically prescribes 2 to 2.5 mg injected under the skin twice a week. A maintenance phase of four to eight weeks follows at about 2 mg once a week or every other week. Some providers have you inject near an injured area, though it works systemically either way. Your provider sets your dose and schedule and adjusts at follow-ups.
TB-500 arrives as a lyophilized powder you reconstitute with the included bacteriostatic water, then keep refrigerated. Your kit includes insulin-type syringes, swabs, and step-by-step mixing instructions, and your care team can walk you through the first dose.
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Join the GobyMeds communityWeeks 1–2. Loading phase begins with twice-weekly doses. Some people notice less overall soreness and a quicker bounce-back from workouts within the first two weeks.
Weeks 3–6. Mobility and comfort at injured areas typically improve as the loading phase completes; this is when most people feel the clearest difference.
Weeks 6–12. Maintenance phase at one dose a week or every other week sustains the effect while tissue continues to remodel.
After the course. Many patients stop once recovered and repeat a course for a new injury; your provider plans the next step at follow-up. A typical path, not a promise.
Most people tolerate TB-500 well. The most common effects are a brief flush or tiredness after a dose, headache, and redness or a small bump at the injection site. In clinical trials of thymosin beta-4 no serious adverse events were attributed to the drug at any dose tested, and no liver, kidney, or heart toxicity was reported. A theoretical concern that thymosin beta-4 could support tumor-cell movement has been raised in laboratory studies and is contested; it is the reason TB-500 is not prescribed to people with cancer. Compounded TB-500 is not FDA-approved. Report side effects to your care team and to the FDA at 1-800-FDA-1088.
Do not use TB-500 if you have active cancer or a history of certain tumors, if you are pregnant, planning a pregnancy, or breastfeeding, or if you have a known allergy to the formulation. Tell your provider about recent surgery, heart conditions, and all medications and supplements you take. Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. Prescription only; not available in all states. Never share needles or vials.
This page is for informational purposes and does not replace a consultation with a licensed provider. Compounded medications are not reviewed by the FDA for safety, effectiveness, or quality. Brand names are trademarks of their respective owners; GobyMeds is not affiliated with them.
Answers from the GobyMeds care team. Still have a question? Ask your provider during your online visit, chat with us on the site, or call +1 866 785 9869 — U.S.-based, around the clock.
TB-500 is a lab-made fragment of thymosin beta-4, a protein found in nearly every cell in your body that helps cells move to where repair is needed. The full protein has been studied in human trials for heart repair and corneal wound healing. At GobyMeds, TB-500 is prescribed as a compounded subcutaneous injection prepared by a licensed U.S. pharmacy. It is not FDA-approved.
Patients most often use TB-500 for recovery from muscle, tendon, and ligament injuries, for stubborn joint inflammation, and for general recovery when training hard. Thymosin beta-4 has also been studied for wound healing, which is the indication the FDA advisory committee reviewed in 2026, and for hair and skin. Human evidence is strongest for the full protein in heart and eye research; most other uses rest on animal data.
TB-500 is usually taken in two phases: a loading phase of about 2 to 2.5 mg twice a week for four to six weeks, then a maintenance dose of around 2 mg once a week or every other week. It arrives as a powder you mix with the included water and inject under the skin with an insulin-type syringe. Your provider sets your dose; this is a typical pattern, not a prescription.
Think of BPC-157 as the local repair signal (blood flow, gut lining, the specific tendon that hurts) and TB-500 as the systemic one (it travels through the body and recruits repair cells wherever they are needed). Many providers prescribe both for musculoskeletal injuries. If your main concern is gut-related, BPC-157 alone is the usual starting point. Your provider will recommend one or both based on your goals.
A typical course runs 8 to 12 weeks: four to six weeks of loading followed by four to eight weeks of maintenance. Many people report improved mobility and less soreness during the loading phase and continued gains through maintenance. Your provider reviews progress at follow-ups and decides whether to extend, pause, or repeat.
Side effects are typically mild: a temporary flush, a brief feeling of tiredness after a dose, headache, or redness at the injection site. In clinical trials of thymosin beta-4 no serious adverse events were attributed to the drug. Because it promotes cell migration and blood-vessel growth, it is not prescribed to people with active cancer. Compounded TB-500 is not FDA-approved.
Yes. TB-500 has been on the World Anti-Doping Agency's prohibited list since 2012. Drug-tested athletes should not use it; tell your provider if you compete.
Peptides are short chains of amino acids, the same building blocks that make up proteins. Your body already makes thousands of them to carry signals between cells: to start repair after an injury, to release growth hormone during sleep, to calm inflammation, or to tell your mitochondria to make more energy. Peptide therapy uses lab-made copies or fragments of those signals, prescribed at a specific dose, to support a process your body already knows how to run. Semaglutide and tirzepatide are peptides too, which is why GobyMeds already has years of experience prescribing and shipping them.
Compounded peptides are not FDA-approved, and no compounded medication is. In July 2026 the FDA's Pharmacy Compounding Advisory Committee voted to recommend adding BPC-157, KPV, TB-500, MOTS-c, Semax, and Epitalon to the list of substances that licensed 503A pharmacies may compound, and in October 2026 HHS published an interim enforcement-discretion policy covering those six peptides while the FDA completes formal rulemaking. GobyMeds offers a peptide only when a licensed U.S. pharmacy can lawfully compound it for your prescription under that policy and your state's rules. Compounded drugs are not evaluated by the FDA for safety, effectiveness, or quality.
Yes. Every peptide at GobyMeds is prescription-only. You complete a short online visit, a licensed U.S. provider reviews your history and goals, usually within one business day, and prescribes the peptide only if it is appropriate for you. The pharmacy then compounds it for your prescription and ships it to your door. If a provider decides treatment isn't right for you, you receive a full refund.
Websites selling "research use only" peptides ship unregulated powders with no prescription, no provider, no sterility testing you can verify, and no one to call when something feels off. GobyMeds is LegitScript-certified: a licensed provider evaluates you first, a licensed U.S. compounding pharmacy prepares your medication to a prescription, and your care team follows up with you throughout. You also get transparent pricing, a supply kit with instructions, and free shipping, with no membership fee.
Most peptides are broken down in the stomach, so the most reliable route is a small injection under the skin with a tiny insulin-type syringe, the same kind used for GLP-1 weight-loss medication. The needle is very fine, the volume is small, and most people say it is easier than expected after the first time. Your kit includes syringes, alcohol swabs, and step-by-step instructions, and your care team can walk you through the first dose. Semax is the exception: it is a nasal spray.
Often, yes. Peptides are frequently prescribed alongside each other (BPC-157 with TB-500 for recovery, for example) and alongside GLP-1 medication, NAD+, sermorelin, or testosterone therapy. Tell your provider about everything you take, including supplements, and they will coordinate the plan and the timing. Your provider will work with you to adjust your medication for your goals.
No lab work is required to start. Your provider reviews your health history during the online visit and may ask for recent results if something in your history warrants it. For a few peptides your provider may suggest baseline bloodwork so progress can be measured, for example fasting glucose or inflammatory markers; that is optional and you can use your own doctor's results.
Your medication ships free from the pharmacy in insulated, cold-chain packaging in as little as 3 days after provider approval; most orders arrive within two to five business days. Injectable peptides arrive as a sterile vial, either ready to use or as a powder with the water needed to mix it, and should be kept in the refrigerator. Nasal sprays are stored according to the label. Full storage and mixing instructions are in your kit and in the patient portal.
Each peptide page shows its plan prices up front. The price you see is the price you pay: it includes the online visit, provider follow-ups, the medication, your supply kit, and shipping. There is no membership fee, no insurance requirement, and no auto-renewal, and you are not charged until your medication ships.
The peptides GobyMeds offers are copies or fragments of molecules your body already makes, and most people experience few side effects. The most common are mild and temporary: redness or a small bump at the injection site, brief flushing, headache, or nausea. Human research on most peptides is still limited, which is why a provider screens your history first and why we are candid about what the evidence does and does not show. Compounded peptides are not FDA-approved. Report side effects to your care team and to the FDA at 1-800-FDA-1088.
If a GobyMeds provider decides a prescription isn't appropriate for you, you receive a 100% refund of the medication price (lab fees, where they apply, are not refunded). Once your order has been sent to our medical partners or to the pharmacy for fulfillment we will do our best to accommodate changes or cancellations, but we can't guarantee them, and in some cases an adjustment or cancellation carries a $50 medical consultation fee.
Because of regulations covering prescription medication, we are unable to accept returned medication for a refund.
No insurance is needed and GobyMeds does not bill insurance. The price you see is the price you pay, with provider consultation and shipping included and no membership fee.
HSA and FSA cards are accepted at checkout, and we can provide a letter of medical necessity if your plan administrator asks for one.
You answer a short health questionnaire and upload a photo ID. A licensed U.S. provider reviews your history, usually within one business day, confirms the treatment is appropriate, and writes the prescription. There is no video call to schedule unless your provider or your state requires one, and unlimited follow-up messaging with your care team in the patient portal is included with every plan.
If you're not a candidate, you'll be told why and refunded in full.
Compounded TB-500 subcutaneous injection, a thymosin beta-4 fragment, to support whole-body tissue repair and recovery, prescribed online.
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